What is the function of the pancreas in rats?
The pancreas is a brownish, flattened gland found in the tissue between the stomach and small intestine. The pancreas produces digestive enzymes that are sent to the intestine via small ducts (the pancreatic duct). The pancreas also secretes insulin which is important in the regulation of glucose metabolism.
What is the target structure of pancreas?
Main Target cells: hepatic, muscle and adipocyte cells (i.e., cells specialized for energy storage). Mechanism of action: Insulin binds to a specific receptor tyrosine kinase on the plasma membrane and increases its activity to phosphorylate numerous regulatory enzymes and other protein substrates.
Where does the body of the pancreas lie?
The pancreas is about 6 inches long and sits across the back of the abdomen, behind the stomach. The head of the pancreas is on the right side of the abdomen and is connected to the duodenum (the first section of the small intestine) through a small tube called the pancreatic duct.
Why is my pancreas not producing insulin?
Type 1 diabetes Without insulin, the cells cannot get enough energy from food. This form of diabetes results from the body’s immune system attacking the insulin-producing beta cells in the pancreas. The beta cells become damaged and, over time, the pancreas stops producing enough insulin to meet the body’s needs.
Where is the pancreas located in a rat?
Rat Pancreas. The pancreas is an essential gland with both endocrine and exocrine functions. The pancreas is located in the first curve of the small intestine (duodenal region) where it attaches to the stomach. To see the pancreas you will need to lift the stomach up and away to locate the mesentary in which the pancreas is located.
What are the functions and histology of the pancreas?
This article will describe the histology and functions of the pancreas, including a clinically relevant condition that you have definitely heard about, called diabetes mellitus. The pancreas is a large, mixed gland composed of five parts: the head, uncinate process, neck, body and tail.
Where are the beta cells located in the pancreas?
There are four main types of cells in the pancreatic islets: B (beta) cells – these cells secrete insulin and constitute about 70% of the islet cells. They are most commonly located in the central part of the islet.
Where are the secretory granules located in the pancreas?
In this low power electron micrograph, observe the organization of the acini, composed of acinar cells. Within the acinar cells you will see the basal rough endoplasmic reticulum and the numerous secretory granules in the apical region of the cells, facing the small lumen of the acinus.