What is gastroesophageal carcinoma?
Gastroesophageal junction adenocarcinoma is a rare type of cancer of the esophagus, the tube that connects your mouth and stomach. It starts in the gastroesophageal (GE) junction, the area where the esophagus and stomach join together. The cancer grows from cells that make mucus.
How does someone get esophageal cancer?
Esophageal cancer occurs when cells in the esophagus develop changes (mutations) in their DNA. The changes make cells grow and divide out of control. The accumulating abnormal cells form a tumor in the esophagus that can grow to invade nearby structures and spread to other parts of the body.
What are the two most common types of esophageal cancer?
Most esophageal cancers can be classified as one of two types: adenocarcinoma or squamous cell carcinoma. A third type of esophageal cancer, called small cell carcinoma, is very rare.
Is GERD cancer curable?
Most often, esophageal cancer is a treatable disease but not a curable one. Patients who have severe Barrett’s esophagus (some consider this stage T0 or precancerous) and those with few cancer cells tend to have relatively successful long-term outcomes.
What kind of cancer is in the gastroesophageal junction?
Gastroesophageal junction adenocarcinoma facts. A gastroesophageal (GE) junction adenocarcinoma is a cancer that begins in cells located near the GE junction, the area where the esophagus (or food tube) connects to the stomach. Gastroesophageal junction adenocarcinomas are staged and treated like cancers of the esophagus.
What causes cancer in the stomach and esophagus?
And cancer cells can break off from the tumor to spread throughout the body. Gastroesophageal junction cancer is associated with having gastrointestinal reflux disease (GERD) and, less strongly, with obesity and smoking. GERD is a condition caused by frequent backflow of stomach acid into the esophagus.
What kind of surgery is done for esophageal cancer?
Esophagectomy is the removal of the cancerous part of the esophagus and nearby lymph nodes. This procedure is performed only on patients with very early cancer that has not spread to the stomach. Esophagogastrectomy is the removal of the cancerous part of the esophagus, nearby lymph nodes, and the upper part of the stomach.
Where does adenocarcinoma start in the esophagus?
Gastroesophageal junction adenocarcinoma is a rare type of cancer of the esophagus, the tube that connects your mouth and stomach. It starts in the gastroesophageal (GE) junction, the area where…