What is calcium phosphate product?
Calcium phosphate product (Ca x Pi) is a clinically relevant tool to estimate the cardiovascular risk of patients with renal failure. In reports, mostly total serum calcium has been used. Fifty-eight healthy individuals and 180 hemodialysis (HD) patients from 2 centers were studied.
What is the normal calcium phosphate product?
In healthy subjects, serum calcium is usually in the range of 8.5–10.5 mg/dL (2.1–2.6 mmol/L) and serum level of phosphorus between 2.5 and 4.5 mg/dL (0.81–1.45 mmol/L) [5].
What is the treatment for calciphylaxis?
A medication called sodium thiosulfate can decrease calcium buildup in the arterioles. It’s given intravenously three times a week, usually during dialysis. Your doctor may also recommend a medication called cinacalcet (Sensipar), which can help control parathyroid hormone (PTH).
Does hyperphosphatemia cause calciphylaxis?
Calciphylaxis is associated with hyperphosphatemia and increased osteopontin expression by vascular smooth muscle cells.
Is calcium phosphate bad?
Is it bad for you? Multiple studies of tricalcium phosphate have shown it to be safe for both human and animal consumption. These studies have concluded that calcium phosphates can aid in bone and mineral regeneration.
What is Calciphylaxis disease?
Calciphylaxis is a type of vascular calcification generally seen in patients with kidney failure. The condition causes skin lesions and severe pain and usually has a high mortality rate. Typically, patients diagnosed with calciphylaxis live about six months.
Does calciphylaxis go away?
At the moment, there isn’t an effective treatment available for calciphylaxis. Current treatment is focused on caring for the skin lesions, preventing infections, and correcting the calcium and phosphorous concentrations in the blood. Treating the wounds and lesions might include: enzymatic debriding agents.
How serious is calciphylaxis?
Calciphylaxis (kal-sih-fuh-LAK-sis) is a serious, uncommon disease in which calcium accumulates in small blood vessels of the fat and skin tissues. Calciphylaxis causes blood clots, painful skin ulcers and may cause serious infections that can lead to death.
How to calculate the calcium-phosphorus product?
Identify the serum calcium level. This is accomplished through blood tests ordered by a physician.
What is the product of calcium and phosphorus?
Just as its name sounds, calcium phosphate is made from a combination of calcium and phosphorus, but several different forms exist and they fill different jobs. One type of calcium phosphate, known as hydroxyapatite, is the primary mineral your body uses to build and strengthen bones and teeth.
What is the relationship between calcium and phosphorus?
Calcium and phosphorus have an inverse relationship, meaning, that if blood calcium levels are high, phosphorus levels will be low. Inversely, if phosphorus levels are high, then calcium levels will be low.