What are polymeric nanoparticles in drug delivery?
Abstract: Polymer nanoparticles (NPs) represent one of the most innovative non-invasive approaches for drug delivery applications. NPs main objective is to convey the therapeutic molecule be they drugs, proteins, or nucleic acids directly into the target organ or tissue.
What are polymeric nanoparticles?
Polymeric nanoparticles are colloidal particles of size range 10 nm–1 μm and solid in nature. Depending on preparation method, polymeric nanoparticles can form two types of structures: nanosphere and nanocapsule. Synthetic polymers used in synthesis come either in prepolymerized form or polymerize during process.
What is the major advantages of polymer in polymeric nano particles?
Most important advantages offered by the polymeric nanoparticles include the following: (1) provide controlled release to the desired site, (2) provide stability to labile molecules (e.g., proteins), and (3) provide ability to modify surfaces with ligands for stealth and targeted drug delivery purposes [30].
How do polymeric nanoparticles work?
Polymeric nanoparticles (NPs) are particles within the size range from 1 to 1000 nm and can be loaded with active compounds entrapped within or surface-adsorbed onto the polymeric core. Polymeric NPs have shown great potential for targeted delivery of drugs for the treatment of several diseases.
What is the major advantage of polymers in polymeric nanoparticles Mcq?
The advantage of polymeric particles is that they can be prepared from renewable materials, and their particle size and constituent can be controlled. Nanoparticles include micron and nanopolymers that are used as carrier particles for vaccines or drugs.
What are the side effects of nanoparticles?
The effects of inhaled nanoparticles in the body may include lung inflammation and heart problems. Studies in humans show that breathing in diesel soot causes a general inflammatory response and alters the system that regulates the involuntary functions in the cardiovascular system, such as control of heart rate.
What are nanoparticles give an example?
In addition, nanoparticles can be classified as hard (e.g., titania [titanium dioxide], silica [silica dioxide] particles, and fullerenes) or as soft (e.g., liposomes, vesicles, and nanodroplets).