What is the endochondral ossification process?
Endochondral ossification is the process by which the embryonic cartilaginous model of most bones contributes to longitudinal growth and is gradually replaced by bone.
What tissues are involved in endochondral ossification?
Endochondral ossification is the process by which bone tissue is formed in early fetal development. It begins when mesenchymal stem cells (MSC’s) start to produce a cartilage template of long bones, such as the femur and the tibia, upon which bone morphogenesis occurs (Ortega et al., 2004).
What are the characteristics of endochondral ossification?
Osteoblasts migrate to the ossification front and synthesize bone matrix. Endochondral ossification is a well-ordered process that has definite polarity with residual cartilage on one edge and newly formed osteoid on the other. Trailing osteoid is mineralized in an orderly fashion to form new mineralized bone.
What is endochondral ossification quizlet?
Endochondral ossification. -a process whereby cartilage is replaced by bone. -forms both compact and spongy bone. Method used in the formation of most bones, especially long bones.
Why is endochondral ossification important?
Endochondral ossification is also an essential process during the rudimentary formation of long bones, the growth of the length of long bones, and the natural healing of bone fractures.
Where does endochondral ossification occur quizlet?
Terms in this set (43) Endochondral Ossification is? Bone that forms in cartilage model.
What is ossification process?
Bone ossification, or osteogenesis, is the process of bone formation. Endochondral ossification begins with mesenchymal tissue transforming into a cartilage intermediate, which is later replaced by bone and forms the remainder of the axial skeleton and the long bones.
What are the steps of ossification?
Endochondral ossification can be summed into 5 major steps: Hypertrophication : Chondrocyte cells grow. Calcification: Hardening of hyalin cartilage matrix. Cavitation: Chrondrocytes die and leave cavities in the bone. Periosteal bud invasion: Nutrients are delivered to the bone via blood vessels, and nerves also enter.
What bones are considered intramembranous?
Bones or parts of bones that develop through the intramembranous ossification process include the collarbones; the patella or kneecap; the parietal, frontal, occipital and temporal bones in the skull; and the upper and lower jawbones. Other specialized structures, such as a turtle’s shell, also develop this way.
What are the steps in bone formation?
The formation of bone during the fetal stage of development occurs by two processes: intramembranous ossification and endochondral ossification. Intramembranous Ossification . Intramembranous ossification mainly occurs during the formation of the flat bones of the skull, as well as the mandible, maxilla, and clavicles.
What is the medical definition of ossification?
Medical Definition of ossification. 1a : the process of bone formation usually beginning at particular centers in each prospective bone and involving the activities of special osteoblasts that segregate and deposit inorganic bone substance about themselves — compare calcification sense a. b : an instance of this process.